Europe’s first syphilis outbreak may predate Columbus’ voyage

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To support our nonprofit science journalism, please make a tax-deductible gift today. In a woodcut, a physician examines the urine of a patient in the first European syphilis epidemic. In the late s, a terrifying disease erupted in Europe, leaving victims with bursting boils and rotting flesh. The syphilis epidemic raged across the continent, killing up to 5 million people. For centuries, historians, and archaeologists have debated the origin of the disease, with some blaming Christopher Columbus and his crew for bringing it back from the Americas.

Today, syphilis and other conditions caused by the same bacterium, Treponema pallidum , such as yaws and bejel, are making a comeback, with millions of people infected every year. By understanding when and where T. Researchers have long clashed over the circumstances of the European syphilis epidemic.

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